Rapid Response Research Solution

Rapid Response Research Centre

COVID-19 Outbreak and Crises Solutions

Considering the long-term effect of COVID-19, we propose to quickly establish a RaReRC to focus on bringing a diverse group of scientists, mathematicians, economists, sociologists, policymakers, educators and the public to put forward a persistent effort to specialise in outbreaks. The centre will excel on topics which are hard to tackle with existing facilities and by conventional means. Keeping this long-term vision in mind, our short-term vision to develop a strategic programme for COVID-19 will be based on COVID-19 PCR Speciality, Low-Cost And Less-Chemically Involved Rapid Diagnosis, Rapid Isolation, Personal Protection, Applied Modelling Integrating Epidemic Test Results, Novel Architecture, Social Integration, Socioeconomics of Pandemic, and Distributed and Insourcing Research. These short-term plan of RaReRC is planned for immediate societal impact where all the sections will have output in terms of one months to six months with an intention of serving the country on COVID-19 until five years with aim of eradicating COVID-19 from the country and prepare ourselves for next outbreaks.

The consortium is created by (from left to right) Dr Moumita Ghosh, Dr Anirvan Chatterjee, Satyajit Mitra, Dr Harish Sasikumar, Prof Jaideep Prabhu, Prof Kasthuri Kannan, Dr Arjuna Sathiaseelan, Dr Abhilash Thendiyammal, Dr M Balasubrahmaniyam, and Dr Siddharth Mitra-Ghosh.

Opensource Single-Virus Microscopy Add-on

Low-cost Less-chemically involved Rapid Biophysical POC diagnosis of COVID-19 .

RaReDeLi /Rapid Response Decent Living: A Unified Multidisciplinary Dashboard Solution for India's Sustainable Socioeconomic Growth

When the world is about to experience the worst recession after the WW-II, have we wondered how to sustainably develop good health, well-being and economics in a weakened/complex socioeconomic condition in India? India is the largest democracy and home of poor billions. The COVID-19 pandemic has brought a humongous problem in India where prior non-uniformly distributed wealth, health and education were prevailing. The 2020-2021 Indian economy is expected to shrink by 3.2% according to the World Bank. The current 'Unlock-I' was intended to ease this economic downfall while on 08/06/2020 2.56K COVID-19 cases have made India as 5th largest affected country. RaReDeLi proposes to develop a unified multidisciplinary/dashboard solutions of essential product marketing in India during and after the pandemic. Globally, India is the second-largest technology market. 90.15% of the Indian population uses mobile phones and 25% uses smartphones. We will create a multidimensional matrix by deploying portable ventilator as a therapeutic technology, sanitiser as a personal protection method, diagnostic sensor, and software for social communication. We will trial technologies being developed for COVID-19 and its dissemination for social development in India. Four kinds of COVID-19 product lines will be trialled for their long-term sustainability.

NanoSMoS: Nanofluidic Single-Molecule Sensitive Sensor for Domestic Spread of Carcinogens and Airborne Pathogens

Disease like cancer and pandemics cause huge long-term economic impact and raises a big question on the survival of human race. Our vision is to make public aware of the root cause of these diseases and empower them to monitor it at home like, a CO sensor but at the ultimate sensitivity. A single molecule of carcinogens and a single pathogen is sufficient to trigger the terminal illness. Many such detrimental compounds and microorganisms can be avoided at early stage. Thus, we aim to develop a domestic pollution sensor to monitor domestic organic carcinogens at single-molecule sensitivity. Since the sensors will be single-molecule sensitive it will be suitable for secondary detection of lethal airborne pathogens and nanoparticles, which falls under particulate matter. The particular need of this sensors are for the low-income housings in densely populated countries and fundamental investigation of material science and molecular biology research.

Early detection and prediction of COVID-19

COVID-19 outbreak requires attention from multilateral collaboration. Science and technology have gone to the level of achievements that diverse background of expertise can come to a table to bring forward solution together in an urgent situation, like COVID-19 outbreak. We would like to translate our scientific understanding of virology, single-molecule detection, single-virus detection, biophysics, optics, statistical physics, electron-optics, and artificial intelligence to eliminate false-negative detections, and thereby, prevent the human-rights violation at South Asian countries. We are proposing to take a novel path of biophysical detection to avoid large costs involved for chemicals and biomolecules in genome analysis-based identification of nCoV. Beside low-cost, the proposed method can identify nCoV in a high throughput manner. We will also reach out to the public to make them understand the need for early diagnosis.

SASMolution: A microbiologically relevant sanitizer

SASMolution is a microbiologically relevant sanitizer that is used in BSL3/CL2 labs where viruses are handled. The solution coagulates protein at an optimal rate so that it can permeate through microbial cells before coagulation can block SASMolution; leading to the entire microbial cell death. The formula used here is most effective in killing microbes. Higher or lower concentration of the solution is not so effective in killing microbes.

SASMolution does not contain any artificially synthesised colour or essence; the added colour and essence are extracted from orange peel and water lily using only biocompatible organic chemistry.

SASMolution is packaged in spray bottles since a similar method is used in the labs as well. It will spray an optimal amount of SASMolution that will also enable large longevity than any conventional sanitisers in the market.

During the public health emergency of international concern, SASMolution is developed and prepared by scientists from the University of Cambridge, Utrecht University, Leiden University and Indian Institute of Technology Bombay under the unique platform of Rapid Response Research Solution of Open Academic Research.

Open Academic Research is registered in the UK as Open Academic Research UK CIC and in India as Open Academic Research Council.

Where is COVID-19 taking us?

Use a laptop or tablet or larger screen and sit properly while analysing the data.